electronic Patient Benefit Index


Quick and easy assessment of

therapy benefit


What is the ePBI?


ePBI is an instrument for dermatological patients and their physicians based on the Patient Benefit Index (PBI). The PBI is used in experimental dermatology to evaluate the efficacy and safety of drugs used for the treatment of psoriasis, while patient reported needs and benefits are collected. It can also be gathered for quality assurance and shared decision making. ePBI is available as a mobile application for Android and iOS devices, as well as a web-based online calculator.


Validation of questionnaire

paper version: yes            digital version: yes

How to use the ePBI

Before the beginning of treatment, the patient completes a questionnaire on their treatment goals (PNQ: Patient Needs Questionnaire) and indicates how important these are to them on a 5-point scale from "not at all" to " very" or whether they do not apply to them. After starting treatment, the patient completes the Patient Benefit Questionnaire (PBQ) and indicates the extent to which the treatment has helped them to achieve the previously listed goals or whether these did not apply to them. Once again, this is rated on a 5-point scale from "not at all" to "very". Finally, the overall benefit of the therapy is calculated from the answers given.


table 1 epbi en

The index range is between 0 (no patient relevant benefit) and 4 (maximum patient relevant benefit).


Below is an example of the PBI calculation process in four steps.




1) Importance of treatment goals


With the help of the following questions, we’d like to know how important the below mentioned goals are to you personally in the current treatment.

For each of the following statements, please mark how important this treatment goal is to you.  If a statement does not apply to you, e.g. because you do not have pain, please mark “does not apply to me“.

step1 re en 4

2) Treatment benefits

Please fill in the type of treatment for skin disease that you are currently undergoing (or which you underwent last):

Treatment:   _____________________________   Since when?:   _____________________

O No treatment of skin disease over the last 12 months (→ please continue on the next page!)


Please mark for each of the following statements how well the goals of the current treatment have already been met and how beneficial the treatment has been. If a statement did not apply to you, e.g. because you had no pain, please mark “did not apply to me”.

pbi treatment benefits

3) Calculation PBI

step4 en 1
scale pbi en

4) View of results (example)

graph pbi en 3

Want to know more?


Structure and scope of the Patient Benefit Index

Want to know more?


Structure and scope of the Patient Benefit Index

The following versions of the ePBI are available

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Endpoint Model: Treatment of Disease X


Food and Drug Administration. Guidance for industry – Patient-Reported Outcome Measures: Use in medical product development to support labeling claims. US Food and Drug administration website, 2009 [cited 2017]

About Patient Reported Outcomes


“A PRO is any report of the status of a patient’s health condition that comes directly from the patient, without interpretation of the patient’s response by a clinician or anyone else.”


“Use of a PRO instrument is advised when measuring a concept best known by the patient or best measured from the patient perspective. […] PRO instrument adequacy depends on its role and relationships with other clinical trial endpoints as depicted in the endpoint model.”


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The intuitive and interactive design of the ePBI ensures easy understanding of all questions, whether for physicians or patients.

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Save time with our online tool. Fill in the questionnaire and your ePBI score will be calculated automatically.

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On DermaValue, you not only get your PBI value, but also learn what it means in terms of your therapy benefit.